A rapid veterinary drug residue examination technique for examining animal products has recently passed the identification in the China Agricultural University. Related experts hold the view that this technique is an important breakthrough in veterinary drug residue examination technique. The project entitled “Study on the Sulfadimidine and Clenbutrol Enzyme-Linked Immune Reagent Kit” is the important content of the research topic of “Study on the Veterinary Drug Safety Evaluation and Residue Examination Technique”, which is a state science and technology strategic plan during the National Tenth Five-Year Plan period.

The domestic authoritative experts in preventive medicine hold the view that the appearance of the rapid test of sulfadimidine and clenbutrol is of great significance. First, it provides forceful inspection means for the state. Second, it is used for food safety guarantee and has active influence in standardizing agricultural husbandry industry in rationally use of veterinary drugs. Third, it is beneficial to the prevention of food-sourced diseases.

At present, “sulfadimidine” is one of the most commonly used veterinary drug antibiotic functions in China, which cause many drug resistances produced by bacteria. In addition, it has the potential of causing canter in human beings. Clenbutrol is a βtype stimulant drug used in livestock and poultry production. The European and American countries and China have listed these two classes of drug into the focus for veterinary drug residue control. At present, the traditional examination method used in China needs advanced equipment with high investment, high coast, and strict and high requirement of operators. Therefore, the traditional method is very different to extend and apply under situation of large-scale production.

The method of rapid Sulfadimidine and Clenbutrol examination technique has adopted “Reagent Kit” method developed by Professor Shen Jianzhong, from the China Agricultural University, has the advantages of small investment, low cost, easy operation, shorter examination time and large-scale examination samples, and is suitable for checking large number of samples. It has enabled large import and export trading companies and large-scale production enterprises become possible to use such rapid examination veterinary drug residue therefore it has broad application prospect in the future. Related experts hold the view that this technique is suitable for the local conditions of China and have autonomous intellectual property right, which has filled in the gaps of domestic science and technology.

After review and application by related institutions, the project of Sulfadimidine and Clenbutrol Enzyme-Linked Immune Reagent Kit” has the advantages of high sensitivity, good precision, more specificity. The examination limit of Sulfadimidine monoclonal antibody Reagent Kit reached 1.3 μg/kg, which is much lower than the Sulfadimidine residue limitation standard (100μg/kg ) of the UN food code committee and the standard formulated by the Ministry of Agriculture. The examination limit of Clenbutrol monoclonal antibody Reagent Kit is 0.1μg/kg, which has reached the examination requirement of the Ministry of Agriculture.

The experts who attended the appraisal conference have a unanimous comment on the innovative research achievement that it has reached the world advanced level.

Source: Chinese Livestock Newspaper,