China’s first animal gene engineering vaccine came out in the Sichuan Agricultural University. This has created a forerunner of practical application of animal virus gene engineering vaccine in China.

According to introduction, pseudo-rabies is an acute infectious disease caused by pseudo-rabies virus in swine, cattle, sheep, goat and many other livestock, poultry, as well as wildlife. Swine is the major host and infectious source of this disease. Swine pseudo-rabies has a world distribution at present time; its epidemic is in an increasing trend, which causes enormous losses to livestock industry.

Through 10 years of conscientious study, Professor Guo Wanzhu from the Sichuan Agricultural University, has taken the lead in unfolding study on the biological and molecular biological characters of pseudo-rabies virus, and successfully constructed a series of pseudo-rabies gene lacking vaccine strain by using lacking, recombination and clone and other gene operational technologies. Recently, one of its landmark achievements is the “Swine Pseudo-Rabies (Gene Lacking) Live Vaccine (SA215 Strain)” has obtained the new state veterinary medicine certificate, thus, it has become the first animal virus gene engineering vaccine in China.

The experimental study and large volume of application effect have proved that this vaccine has the characters of stable genetics, fine safety, stronger immunogenicity, and unique capacity against incubation infections as compared with conventional vaccines and vaccines of the same category, and has reached the application standard of vaccines of the same category in the world.

Authoritative experts hold the view that this achievement has played a decisive role in the implementation of prevention and control measures against pseudo-rabies and the final eradication of pseudo-rabies in China.

Source: www.cav.net.cn